Subtle Medical Advances GenAI Innovation in Radiology with NVIDIA
Leveraging NVIDIA’s Latest GPU Architecture to Accelerate Innovations in Ultra-Low-Dose Imaging and Enhanced Lesion Visualization
MENLO PARK, Calif. – March 18, 2025 – intelligence is transforming radiology by enabling faster, safer, and more precise imaging. At the core of this revolution lies NVIDIA’s latest generation GPU architecture, a critical enabler for training and deploying state-of-the-art generative AI models. Leveraging this hardware, Subtle Medical has developed innovative GenAI solutions that dramatically reduce radiation doses and enhance lesion visualization, ultimately reshaping clinical practice.
Solving The Challenge in Radiology Imaging with GenAI and NVIDIA Accelerated Computing
Medical imaging today faces several critical challenges. Imaging modalities such as MRI, PET, and CT exams, are used in over five hundred million patients annually for diagnosis and treatment, involving long scan times and/or high radiation/contrast dosage. This not only compromises the patient experience, causing delays of care, but also burdens healthcare facilities with high operational costs. Furthermore, variability in image quality—especially in lesion visualization—can lead to diagnostic inconsistencies and hinder effective treatment planning. These issues around radiology data acquisition, which account for ~80% of imaging cost, are particularly acute when resources are constrained and where access to high-quality imaging remains limited.
Subtle Medical, the vertical leader in AI-powered imaging, has developed state-of-the-art GenAI solutions that address pressing clinical needs such as speeding up radiology exams, reducing radiation dose, optimizing contrast dose, and enhancing lesion visualization. Obtaining 9 FDA clearances and serving multiple millions of patients worldwide, Subtle Medical has deployed its AI products, such as SubtleHD, SubtleMR, and SubtlePET, to more than 900 hospital and imaging center sites globally to solve the pain point of quality and efficiency in radiology exams with up to 5x faster scans.
Subtle Medical drives cutting-edge AI innovation with NVIDIA.
Subtle Medical’s integration of NVIDIA technology has been instrumental in advancing AI-driven medical imaging and enhancing efficiency in model training, deployment, and clinical impact. As one of the first NVIDIA Inception Startups and a winner of the NVIDIA Inception AI Award in 2018, Subtle Medical has pioneered the adoption of NVIDIA DGX systems, NVIDIA TensorRT/Triton, and NVIDIA accelerated computing to optimize imaging solutions.
Key Highlights:
Early Innovation & Recognition – Subtle Medical was one of the first NVIDIA Inception Startups and an early adopter of NVIDIA DGX, NVIDIA V100 Tensor Core GPUs, and TensorRT/Triton in medical imaging.
Accelerated AI Development – NVIDIA’s cutting-edge GPU technology significantly improves training and deployment efficiency for AI-powered imaging solutions.
Award-Winning AI Innovation – Subtle Medical was awarded one of the NVIDIA H100 GPUs after winning the Stanford-HealthUnity GenAI in Healthcare competition, sponsored by NVIDIA and SuperMicro, enabling further advancements in AI model training.
Industry-Leading Benchmarking Next-Gen Performance – Systematic testing on tasks such as virtual contrast dose synthesis for oncology imaging and pre-contrast T1 MRI optimization demonstrates up to 6x efficiency gains in training and 4.4x faster inference speeds. Integration of H100 servers for faster training and deployment, further advancing Subtle Medical’s competitive edge.
“By leveraging NVIDIA state-of-the-art hardware and software, including Triton/TensorRT, Subtle Medical continues to set new standards in AI-powered imaging, ensuring superior efficiency, speed, and diagnostic precision across healthcare,” said Ajit Shankaranarayanan, PhD, Chief Product Officer at Subtle Medical.
Real-world impact of GenAI solutions
Since the first FDA clearance of SubtleMR in 2019, Subtle Medical has introduced multiple AI/GenAI-powered products with 9 total FDA clearances. For example, SubtleSYNTH, FDA-cleared in 2024, is the first approved synthetic data generation clinical product powered by AI. Contrast dose optimization, which has been in partnership with pharmaceutical industry leaders such as Bayer and Bracco, has also started to make its way into real clinical applications.
Subtle Medical’s GenAI solutions are designed to overcome traditional imaging limitations:
Ultra-Low-Dose Imaging: Subtle’s advanced algorithms enable up to a 75% reduction in imaging radiation dose without compromising quality, making scans safer for patients.
Enhanced Lesion Visualization: Virtual augmentation techniques significantly improve the clarity and delineation of lesions, thereby boosting diagnostic confidence and precision.
State-of-the-Art Image Reconstruction: By standardizing and enhancing imaging data, Subtle’s AI models deliver consistent, high-quality images that form the backbone of effective clinical decision-making.
Unprecedented Speed: With up to 5x faster scans, imaging institutions can reduce patient wait times, increase scanner throughput, and improve overall imaging efficiency with existing resources.
“The combined power of our GenAI solutions and NVIDIA’s GPU architecture is already making a real impact in clinical practice,” said Enhao Gong, PhD, Co-Founder and CEO at Subtle Medical. “Faster and safer imaging means quicker diagnoses and enhanced patient care, while reduced radiation exposure minimizes risk—especially for pediatric and elderly patients who struggle with long scan times.”
The combined power of our GenAI solutions and the NVIDIA GPU architecture is already making a tangible difference in clinical practice:
Better Clinical Care: Faster, safer imaging processes lead to quicker diagnoses and enhanced patient care, while reduced radiation exposure minimizes patient risk. It also enables a better patient experience through shorter scan durations, especially for pediatric and elderly patients who have a hard time holding still.
Operational Efficiency & Sustainability: Our solutions improve performance on existing machines, reducing the need for costly hardware upgrades and lowering operational costs.
Increased Revenue & Smarter Business Practices: By enabling shorter scan durations, imaging centers can add more patient slots per day, increasing throughput without additional capital investment—and reducing wait times for critical imaging procedures.
Market Potential: With deployments in 900+ sites globally, our technology is expanding access to high-quality diagnostics and driving the future of precision medicine.
The integration of NVIDIA Hopper GPUs with Subtle Medical’s GenAI solutions addresses the critical challenges of high radiation doses, long scan times, and inconsistent image quality. This powerful synergy enables significant acceleration of the development and delivery of AI solutions for ultra-low-dose imaging and enhanced lesion visualization. It also improves the patient experience and outcomes by driving operational efficiency and broadening diagnostic accessibility globally. With robust partnerships and a commitment to continuous innovation, we look forward to redefining the future of medical imaging—delivering safer, faster, and more accurate diagnostics that transform patient care around the world.
Attend the Aunt Minnie webinar on Subtle’s newest MRI package, Subtle-ELITE™, taking place on March 19, 2025, at 10am PT / 1pm ET. Register Now
About Subtle Medical
Subtle Medical is a leading provider of AI-powered imaging solutions designed to enhance the efficiency, quality, and accessibility of medical imaging. Recognized as a CB Insights GenAI 50 company and a two-time CB Insights Top AI 100 and Digital Health 150 company, Subtle Medical is committed to advancing healthcare through AI-driven innovation. Its solutions are deployed worldwide, helping imaging centers and hospitals optimize workflows, improve scanner sustainability, and improve patient care. For more information, visitsubtlemedical.com.
