SubtleMRTM

Improved image quality and efficiency on your existing MRI scanners.

SubtleMR™ is a software solution that improves the quality of accelerated MRI images using sharpness enhancement and denoising.

  • Applicable for 99% of all MRI procedures
  • Can be used with any scanner and field strength
  • Easy implementation with no change in workflow

One of the most exciting things about deep learning reconstruction is how it redefines the usual negotiation between exam time and image quality. This could lead to significant downstream value for imaging operations and for patient experience.

— Christopher Hess, MD, Chair of the Department of Radiology and Biomedical Imaging at UCSF

As Acquired

SubtleMR Enhanced

Improved quality

SubtleMR applies two methods of image enhancement — denoising and increased sharpness — to improve image quality.

Better for patients

Artifact ridden images and the need for re-scans are a challenge for both physicians and patients, especially those who have difficulty holding still for long periods of time. SubtleMR improves the quality of these suboptimal scans.

Ease of use

SubtleMR fits seamlessly into your current workflow. SubtleMR sits between the scanner and PACS. Images are sent from the scanner and are processed by SubtleMR within seconds. The high-quality images are then sent back to PACS and/or other workstations.

Broad applicability

SubtleMR is compatible with any brand or model MRI scanner and field strength with no change in workflow. It can be used to reduce image noise for the entire body, including but not limited to: Head, spine, neck, abdomen, pelvis, prostate, breast and musculoskeletal regions of the body, and is also used to increase image sharpness for head MRI.

SubtleMRTM
Case Review

SubtleMR™ is an AI-based software used to improve MRI image quality using increased sharpness and denoising.

Original Scan

Accelerated Scan

Accelerated Scan enhanced by SubtleMR™

Original Scan

Accelerated Scan

Accelerated Scan enhanced by SubtleMR™

SubtleGADTM

SubtleGAD™
AI-powered for safer MRI*

At Subtle Medical, we’re dedicated to developing innovative healthcare solutions that put patient safety and wellbeing first. SubtleGAD™ (currently in the investigational stage) is a software that uses state-of-the-art deep learning technology to enable a 90% dose reduction of GBCAs (Gadolinium based contrast agents) for contrast-enhanced MRI exams while maintaining excellent image quality. There are more than 30 million contrast-enhanced MRI exams performed each year. When lower gadolinium dosage is administered for any reason, SubtleGAD software can improve image quality, diagnostic accuracy and lesion detectability. The software is compatible with any brand of MRI scanner and PACS and seamlessly integrates into the current workflow.

Award-Winning Research

Subtle’s newly patented technology was initially invented in 2017 and published in 2018 by researchers from Stanford University demonstrating feasibility. It was highlighted by RSNA as one of the key advances of the year and won an RSNA research prize. Subtle received a $1.6 million SBIR NIH Grant in 2019 to pursue research of SubtleGAD™, and in 2020, Phase II funding was awarded based on the results achieved during Phase I, as well as the scientific and technical merit of the project.

Better Patient Care

The ability to reduce gadolinium dosage by 90% when combined with SubtleGAD™ software addresses real and perceived safety and liability concerns for patients and imaging institutions around the long term effects of GBCAs used in contrast-enhanced MRI procedures.

Lowering contrast dosage has the potential to benefit tens of millions of patients, including pediatric and neonatal patients, as well as patients with chronic neurological diseases such as multiple sclerosis (MS) who have frequent contrast-enhanced MRI exams. Other potential applications include breast MRI studies, used for screening and diagnostic studies in patients with dense breasts, patients with advanced chronic kidney disease (CKD) or marginal kidney function issues who cannot currently undergo full-dose contrast-enhanced MRI, and other patients with concerns about gadolinium retention in the body.

About Subtle Medical

Subtle Medical, Inc. is a healthcare technology company with deep learning solutions that increase the quality and efficiency of medical imaging. It was named CB Insights Top AI 100 and Digital Health 150 company in 2020 and is an Nvidia Inception Award Winner. Current clinical partners include UCSF, Hoag Hospital, Mount Sinai, Sickkids, Radnet, DASA, Tiantan Hospital, and Middlesex Hospital, among others. Subtle is currently in collaboration with top-tier medical device vendors, including Siemens Healthineers, Philips (China) and several pharmaceutical partners. For more information, please visit subtlemedical.com or email sales@subtlemedical.com.

*Information on this page is for research, scientific, and educational purposes. All statements, data and results presented in these publications should be considered for investigational use.

SubtlePETTM

Improved quality and efficiency on your existing machines.

SubtlePET is an AI-powered software solution that denoises images conducted in 25% of the original scan duration.

  • Easy implementation 
  • No change in workflow
  • Compatible with any brand or model scanner
PET Scan Image

Want to see more? Visit our SubtlePET case study

Improved quality

SubtlePET applies denoising to improve the image quality from scans conducted in 1/4th the original scan duration, maintaining diagnostic image quality equivalent to the ground truth image.

Better for patients

SubtlePET improves the quality of accelerated scan protocols so you can get patients out of the scanner back to doing the things they love.

Improved workflow

SubtlePET improves the quality of accelerated scan protocols enabling an optimized workflow.

Extended lifespan

SubtlePET is a virtual upgrade to your existing fleet so you don't need to purchase new and expensive PET scanners, extending the life of your existing machines.

Fewer potential rescans

SubtlePET improves the image quality of sub-optimal scans.

Ease of use

SubtlePET fits seamlessly into your current workflow and takes less than <24 hours to deploy. SubtlePET sits between the scanner and PACS. Images are sent from the scanner and are processed by SubtlePET within seconds. The high-quality images are then sent back to PACS and/or other workstations.


“Our goal at Precision Imaging Centers is to deliver the best patient care possible. We pride ourselves on being early adopters of innovative technology, which differentiates us from other imaging centers. Using SubtlePET, we are able to maintain superior image quality of our accelerated protocols. It also allows us to complete more CT’s on the same scanner. The ability to conduct these faster scans both increases our workflow efficiency and creates a better patient experience by getting patients in and out of the scanner faster. It’s a win-win for us and for them.”

— Dr. Adam Brochert, MD, MBA Radiologist, Precision Imaging Centers

SubtlePETTM
Case Review

SubtlePET applies denoising to improve the image quality from scans conducted in 1/4th the original scan time.

Please complete a simple request to view this case review. Request access

Want to Learn More?

Contact Us